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Dr. Salim Merali

1. Duan X, Kelsen SG., Clarkson AB Jr, Ji R, Merali S, SILAC analysis of oxidative stress-mediated proteins in human pneumocytes: new role for treacle. Proteomics 2010 Jun; 10(11):2165-74, PMID:20340163.

2. Han Z, Liang CG, Cheng Y, Duan  X, Zhong  Z, Potireddy S, Moncada C, Merali S, Latham KE, Oocyte spindle proteomics analysis leading to rescue of chromosome congression defects in cloned embryos. Journal of Proteome Research 2010 Nov 5; 9(11):6025-32, PMID: 20883044.

3. Skelly, M, Merali S, Clarkson AB, Pneumocystis pneumonia and S-adenosylmethionine plasma levels. Journal of Infection 2011 Jun; 62(6):490-92, PMID:21605909.

4. Boden G, Merali S, Measurement of the increase in endoplasmic reticulum  stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals. Methods in Enzymology 2011; 489:67-82, PMID:21266224.

5. Boden G, Song W, Duan X, Cheung P, Kresge K, Barrero C, Merali S, Infusion of glucose and lipids at physiological rates causes acute endoplasmic reticulum stress in rat liver. Obesity (Silver Spring) 2011 Jul; 19(7):1366-73, (Cover page), PMID: 21475143.

6. Perez -Leal O, Moncada C, Clarkson AB, Merali S,  Pneumocystis S-adenosylmethionine transport: a potential drug target. American Journal of Respiratory Cell and Molecular Biology 2011 Dec; 45(6): 1142-46,PMID: 21642588.

7. Kelsen SG, Merali S, Cigarette smoke-induced oxidant stress in the lung, the unfolded protein response, and COPD. Current Respiratory Medicine Reviews 2011; 7(5):384-387.

8. Perez-Leal O, Merali S, Regulation of polyamine metabolism by translational control. Amino Acids 2012 Feb; 42(2-3):611-17.PMID:21811825.

9. Perez-Leal O, Barrero CA,  Clarkson AB, Casero RA, Merali S, Polyamine Regulated Translation of Spermidine/Spermine-N1-Acetyltransferase. Molecular and Cellular Biology 2012 Apr;32(8):1453-67. PMID: 22354986.

10. Lu M *, Merali S*, Gordon R, Jiang J, LiY, MandeliJ, Duan X, Fallon J, HollandJF, Prevention of Doxorubicin Cardiopathic Changes by a Benzyl Styryl Sulfone in Mice. Genes and Cancer 2012 Oct;2(10):985-92.

11. Patel BB, Barrero CA, Braverman A, Kim PD, Jones KA, Chen DE, Bowler RP, Merali S, Kelsen SG, Yeung AT. Assessment of Two Immunodepletion Methods: Off-Target Effects and Variations in Immunodepletion Efficiency May Confound Plasma Proteomics. J Proteome Res. 2012 Dec 7; 11(12):5947-58.PMID: 23082855.

12. Steen HC, Nogusa S, Thapa RJ, Basagoudanavar SH, Gill A, Merali S, Barrero CA, Balachandran S, Gamero AM. Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses. J Biol Chem. 2013 Jan 4;288(1):747-58. PMID: 23139419.

13. Perez-Leal O, Abu-Gharbia, Gordon J, Childers W. E. and Merali S, A novel assay platform for the detection of translational modulators of spermidine/spermine Acetytransferase. Current Pharmaceutical Design 2013 May 16.[Epub ahead of print] PMID: 23701549

14. Barrero CA, Datta PK, Sen S, Deshmane S, Amini S, Khalili K, and  Merali S. HIV-1 Vpr modulates macrophage metabolic pathways: A SILAC-based quantitative analysis PLOS ONE 2013 Jul 12;8(7):e68376. PMID: 23874603.

15. Perez-Leal O, Barrero CA, and Merali S. Translational control of Nrf2 within the open reading frame. Biochem Biophys Res Commun. 2013 Jul 19;437(1)134-9. PMID: 23806685.

16. Liu C, Perez-Leal O, Barrero C, Zahedi K, Soleimani M, Porter C, and Merali S. Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis.Amino Acids. 2013 Jul 24. [Epub ahead of print]. PMID: 23881108.

17. Barrero CA, Perez-Leal O, Aksoy M, Moncada C, Ji R, Lopez Y, Mallilankaraman K, Madesh M, Criner GJ, Kelsen SG, and Merali S Histone 3.3 participates in self-sustaining cascade of apoptosis that contributes to the progression of COPD. Am J Respir Crit Care Med. 2013 Sep 15:188(6):673-83. PMID: 23924319.

18. Merali S, BarreroC, Duan X, MurphyJ, BowlerR, Chen D, CrinerG, BravermanA, MidicU, ObradovicZ, YeungA, KelsenSG. Analysis of the Plasma proteome in COPD:  Novel Low Abundance Proteins Reflect Lung Remodeling. COPD Journal. 2013 Oct 10. PMID: 24111704.

19. Boden G,  Cheung P, Salehi S,  Homko C, Loveland-Jones C, Jayarajan S, Stein P, William K, Liu M, Barrero C,  and Merali S. Insulin regulates the unfolded protein response (UPR) in human adipose tissue. Diabetes 2013 October 15, PMID: 24130338.

20. Morada M, Pendyala L,  Wu G,  Merali S, and Yarlett N, Cryptosporidium parvum Induces an Endoplasmic Stress Response in Intestinal Adenocarcinoma HCT-8 Cell Line. Journal of Biological Chemistry 2013 Oct 18; 288(42):30356-64. PMID: 23986438.

Temple University
Moulder Center for Drug Discovery Research

Temple University School of Pharmacy
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Philadelphia, PA 19140